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Page Background 16.001 SimpleProbe ® and LightCycler ® are trademarks from Roche. Homogenous amplification methods with real-time detection are covered by patents owned by Roche Molecular Systems, Inc. and F. Hoffmann-La Roche Ltd. SimpleProbe ® probes under license of Roche (for research use only). The less common T-allele (darker eye color) of rs12913832 is associated with an uveal melanoma protective effect from: Genetic markers of pigmentation are novel risk loci for uveal melanoma. Ferguson et al., published 08 Aug 2016 / SNP on Demand More and more human SNPs are analyzed for their potential association with diseases, risk factors and predispositions. Our LightSNiP assays are pre- established, probe-based tests using a melting curve to detect sequence variations. These assays are developed on a Roche LightCycler ® 480 system, but can be applied also on other instruments that run a melting curve – guaranteed for all LightCycler ® systems 1, 2.0, Nano and Roche 480 instruments. They have been exemplarily tested to work on MyGo, Bio-Rad CFX96, Rotorgene and other instruments. Convenient to Apply LightSNiP assays come premixed with a standardized protocol. Just reconstitute in water, combine with the Roche master reagent, add samples and start your expe- riment. LightSNiP assays on pla- tes (arrays) available on request. Simple to Order For ordering use the rs number from dbSNP (NCBI/GenBank ® ) One vial contains primers and probes for 96 rxns each 20 µ l. LightSNiP Assays DEUTSCHLAND TIB MOLBIOLGmbH Email: Tel. +49 30 78 79 94 55 Fax +49 30 78 79 94 99 USA TIB MOLBIOL LLC Email: Tel. +1 (877) 696-5446 Fax +1 (877) 696-5456 WWW. T I B -MOLB IOL . COM ESPAÑA TIB MOLBIOL sl Email: Tel. +34 91 344 6642 Fax +34 91 344 6670 ITALIA TIB MOLBIOL s.r.l. Email: Tel. +39 010 362 83 88 Fax +39 010 362 19 38 didn't know that rs12913832 is associated with melanoma risk